In the News

Use of low-dose methotrexate is associated with small to moderate elevations in risks for skin cancer and gastrointestinal, infectious, pulmonary, and haematologic adverse events, according to a study published in the Annals of Internal Medicine. Methotrexate is the most commonly used drug for...
Amlodipine lowered long-term gout risk, compared with lisinopril or chlorthalidone, in older adults with hypertension, according to a study published in the Journal of Hypertension. “Our study is clinically relevant as the prevalence of gout has been rising in the United States and the number of...
Researchers have identified the cause of a mysterious illness that has affected 3 families over the past 20 years, and have termed the new disease Cleavage-Resistant RIPK1-Induced Autoinflammatory (CRIA) Syndrome. Daniel Kastner, MD, National Human Genome Research Institute (NHGRI), part of the...
Heart disease is an independent risk factor for severe adverse skin reactions in patients taking allopurinol for gout, according to a study published in CMAJ. A previous study found an association between heart disease and increased risk of hospitalisation for allopurinol-related severe skin...
The US Food and Drug Administration (FDA) has approved rituximab (Rituxan) injection to treat granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) in children aged ≥2 years in combination with glucocorticoids. This is the first approved treatment for children with these rare...

Conference Reports

By Jill Stein

PARIS -- April 9, 2019 -- Children with X-linked hypophosphataemia (XLH) experience larger improvements in rickets and other outcomes when treated with the investigational agent burosumab than with conventional treatment, according to a study presented here at the 2019 World...

By Jill Stein

PARIS -- April 8, 2019 -- Achieving a higher SARC-F score at the time of admission to general rehabilitation is associated with increased functional dependence, according to results of a cross-sectional study presented here at the 2019 World Congress on Osteoporosis,...

By Jill Stein

PARIS -- April 8, 2019 -- Burosumab significantly reduces measures of osteomalacia in adults with X-linked hypophosphataemia (XLH), according to results of a phase 3, open-label, single-arm study reported here on April 5 at the 2019 World Congress on Osteoporosis,...

By Jill Stein

PARIS -- April 8, 2019 -- Patients with osteoporosis or osteopaenia should steer clear of yoga poses that call for hyperflexion and hyperextension of the spine, according to results of a retrospective analysis stated here on April 5 at the 2019 World Congress on Osteoporosis...

By Jill Stein

PARIS -- April 8, 2019 -- Increased adherence to a Mediterranean diet is associated with a decreased risk of worsening pain and symptomatic knee osteoarthritis (OA), according to results of an observational longitudinal study presented here on April 5 at the 2019 World...

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